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Propecia/Finasteride

Herbal Alternative to Propecia® Propecia Before
  & After		 Quotes from men using Propecia  2 year Clinical Studies 5 year Clinical Studies
STUDY DESIGN

Combination of two two-year Phase III pivotal vertex studies (U.S. and International)

Initial Study: (Year 1)
  1,553 men, age 18 to 41
  Mild to moderate, but not complete, hair loss in the vertex
  88% Caucasian, 6% black, and 6% other (Hispanic, Asian, and other)
  For study control, all men were asked to use a specified medicated, tar-based shampoo (Neutrogena T/Gel®) for the prevention of seborrheic dermatitis

24 month data

Efficacy was evaluated by four endpoints:

  Hair count — computer-assisted, macrophotographic hair count in a one-inch diameter circle at the leading edge of the thinning area of the vertex of the scalp
  Patient self-assessment questionnaire
  Investigator assessment
  Assessment of global photographs by an expert panel of dermatologists

Macrophotograph

Randomized Extension Study: (Year 2)

  The 24-month data presented in this piece depict results for the finasteride/finasteride and placebo/placebo groups only

*Neutrogena T/Gel is a registered trademark of Johnson & Johnson.
Additional clinical information

A one-year Phase III study in the anterior mid-scalp with an open extension for an additional year

326 men with mild to moderate hair loss in the anterior mid-scalp with or without vertex balding (modified Norwood/Hamilton Stages 2, 2v, 2a, 3, and 3v, as shown)
   
Parallel design to the two vertex studies with the same study endpoints except:
— Hair count taken in a 1-cm2 circle
— Placebo patients crossed over to PROPECIA for the extension study
   

Modified Norwood/Hamilton Scale

Modified Norwood/Hamilton Classification

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